![]() This leads to an increase of norepinephrine in the brain and helps to control the main symptoms of ADHD.Ī cumulative review of 50 clinical studies that examined the efficacy of atomoxetine showed that it is effective in treating ADHD symptoms in both children and adults. However, researchers believe that it inhibits the reabsorption of norepinephrine, a neurotransmitter that boosts focus. ![]() It isn't clear how atomoxetine works to limit ADHD symptoms. There are currently three non-stimulant ADHD medications that the FDA has approved for adults and children: atomoxetine, clonidine, and guanfacine.Ītomoxetine, which is usually marketed under the brand name Strattera, was the first non-stimulant ADHD medication to be approved by the FDA in 2002. It's a subtle difference, but the important thing to note is that this makes Atomoxetine less likely to be addictive," says Shah. "Unlike stimulant medication which increases the amount of neurotransmitters like dopamine in the brain, non-stimulants like Atomoxetime keep the already existing receptors fired for longer. These chemicals help people with ADHD to maintain focus and reduce symptoms of hyperactivity and impulsivity. Stimulants work by increasing the production of dopamine and norepinephrine in the brain. Moreover, stimulants and non-stimulants affect the brain differently. Shah, MD an Assistant Professor of Psychiatry at Columbia University Irving Medical Center. Non-stimulant medications, on the other hand, are not as potent but are less likely to cause side effects and don't have any addiction potential," says Ravi N. "While stimulants are stronger and work better, they are more likely to cause addiction and side effects. Stimulants are usually the first line of treatment for ADHD, but as of the early 2000s, research shows that an estimated 30% to 50% of treated children and adults discontinue stimulant medication due to adverse effects or inadequate response.
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